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Zhan C, ... Hu X（胡学博）. Cytochrome P450 CYP716A254 catalyzes the formation of oleanolic acid from β-amyrin during oleanane-type triterpenoid saponins biosynthesis in Anemone flaccida. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1271-1277.
发布人：石乐发布时间：2020-07-05

Zhan C, Ahmed S, Hu S, Dong S, Cai Q, Yang T, Wang X, Li X, Hu X（胡学博）. Cytochrome P450 CYP716A254 catalyzes the formation of oleanolic acid from β-amyrin during oleanane-type triterpenoid saponins biosynthesis in Anemone flaccida. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1271-1277. 

【点评：来源于鄂西特有药材地乌有很好的抗炎效果，转录组测序表明这个CYP基因对形成三萜皂苷很关键，我们很努力进行了功能验证，但该酶并不是太高效。后续有待系统研究。】


上一篇：Jafari M, ... Hu X（胡学博）. Genetic diversity and biogeography of T. officinale inferred from multi locus sequence typing approach. PLoS One. 2018 Sep 18;13(9):e0203275.

下一篇：Ahmed S, ... Hu X（胡学博）. Characterization of Anti-bacterial Compounds from the Seed Coat of Chinese Windmill Palm Tree (Trachycarpus fortunei).Front Microbiol. 2017 Oct 4;8:1894.

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